The rumor involved Pfizer (PFE) being the acquirer. You can incur substantial financial losses in any trade or investment. Sold Tercica to Ipsen: Mr. King served as President and General Manager of Tercica. Are some major acquisitions on the way in the biopharmaceutical industry this year? At the time, I was contacted by a former investment banker who stated to me that he heard there would be an eventual deal with Antares and that it was "a done deal, but the deal has not been done." Sold Conceptus to Bayer: Mr. Chung served as the Chief Commercial Officer at Conceptus. 06-01-2023. Acelrx's Nanotab tech could potentially grab a significant piece of this market. ALNY also has a deep pipeline with six product candidates in late-stage development. Keith Speights: All right, Brian. Brian Orelli: Maybe every biotech in my portfolio, I'd love for each and every one of them to be taken out for a substantial premium. Here's a look at the 10 top takeover targets. The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc. 2023, Nasdaq, Inc. All Rights Reserved. Type a symbol or company name. Any you had ideas about? 8. I'm not sure. Gilead Sciences (GILD -1.00%) also has not been shy about making smaller deals. If the letter of intent to acquire your company has been signed, you might be asking what happens next. Source: Mongkolchon Akesin / Shutterstock.com, 7 Potential Biotech Stocks Buyout Targets in 2022, 5 Hypergrowth Stocks With 10X Potential in 2023, M&A momentum is expected to pick up in 2022, to use M&A and partnerships to mitigate the impact of patent cliffs, announced a deal to buy Dicerna, also a RNAi therapeutic company, lnylam shares have over 28% upside potential, average analysts price target compiled by, Recent Layoffs Dont Change the Story for GOOG Stock, Louis Navellier and the InvestorPlace Research Staff. Whether M&A activity continues will have a significant effect on which startups and drug programs get funded and advanced. Abbott Laboratories bought out Solvay Pharmaceuticals for $6.1B. Click to get this free report Alnylam Pharmaceuticals, Inc. (ALNY) : Free Stock Analysis Report Biogen Inc. (BIIB) : Free Stock Analysis Report BioMarin Pharmaceutical Inc. (BMRN) : Free Stock Analysis Report Adaptimmune Therapeutics PLC (ADAP) : Free Stock Analysis Report CRISPR Therapeutics AG (CRSP) : Free Stock Analysis Report To read this article on Zacks.com click here. Best Penny Stocks . This biotechnology company, which operates in hemophilia and ultra-orphan disease drug space, has seven approved treatments, a strong pipeline, and steadily growing revenue. Disclosure: I am long ATRS, SLTM, ACRX. We at Biotech Investments see several catalysts that could make Intra-Cellular Therapies an interesting acquisition target. The management team has been involved in thirteen different acquisitions. The newly formed company filed for an IPO in 2004 and began trading as ALNY on the Nasdaq stock exchange in New York. The company has three marketed products and boasts of a vibrant pipeline, with a host of investigational therapeutics. The FDA has accepted the new drug application for adagrasib in NSCLC, with a PDUFA goal date of Dec. 14, 2022. All rights reserved. Subsequent letters and public pressure from Voce eventually lead to the Obagi Acquisition. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. The speculation gained further ground when Denmark-based Novo Nordisk (NYSE:NVO) announced a deal to buy Dicerna, also a RNAi therapeutic company. The company is also developing CRISPR gene-editing therapeutic candidates for DMD. Freight. Get biopharma news like this in your inbox daily. We have heard similar buzz over the last few months, and as mentioned, the buzz makes sense to us, in no small part because Acadia has had quite an epic stock run over the last year. AMAG Pharmaceuticals (Market Cap $0.7bn) US specialty firm AMAG Pharmaceuticals Inc. is viewed as an acquisition target for companies established in women's health - specifically Novartis AG - due to the potential of bremelanotide in hypoactive sexual desire disorder (HSDD). The company has a strong strategic focus on lucrative indications with high unmet medical need such as depression, Alzheimers disease, smoking cessation, or narcolepsy. To make the world smarter, happier, and richer. We believe there is merit to the current rumors surrounding AcelRx. There were a few, but not as many. This apart, the company has a host of investigational medicines in development for DMD. Over the last few years, pharmaceutical M&A hit record highs as larger companies turned again and again to young biotechs for innovation. In this Motley Fool Live video recorded on Oct. 13, Fool contributors Keith Speights and Brian Orelli discuss potential biotech buyouts that would be great for investors. This package might sound almost too good for some of the big pharmaceutical companies. Now, it is three years since the PARP inhibitor has been approved. Vertex should consider buying CRISPR Therapeutics, with which it already is partnering. Are you interested in learning more about small- and mid-cap biotech stocks with exceptional growth potential and some of the hottest takeover targets of the industry? The downside is that I'm not really sure Vertex wants to get into the CAR-T business, which is basically the other half of CRISPR's clinical pipeline. . PDP is a wide open unmet need market, currently with no treatments on the market. But Brian, is there a biotech buyout that you would really like to see? Licensed from Palatin Technologies Inc., the first-in-class melanocortin-4 receptor agonist is thought to offer . Someone is "mistaken" here. It's in phase 1, so we don't really know how well it works yet. Places you can follow Scott are: www.stockmatusow.com www.twitter.com/StockMatusow @StockMatusow http://www.facebook.com/TheScottMatusowShow Places to follow Dan are: https://twitter.com/biosleuth. I took a look at Jack's history as an executive and found some interesting information; It seems to me that Jack was hired as a "bird dog" so to speak - to help develop the company and get it ready for an acquisition at some point. In addition, the American company has several commercial and research successes, including recent positive Phase 3 clinical trial data for its ATTR amyloidosis drug ONPATTRO (Patisiran). Medarex bought out GenPharm for $65M. For those with multiple focuses, the chosen therapeutic area is based on lead asset or, lacking one that's distinctly identified, the company is classified under "other.". Tripos International bought out Pharsight for $57M. I also agree with you that Vertex, if there's going to be one of those massive big pharma mergers like we've seen over the last 20 years, some of those massive deals, I think Vertex would be an excellent candidate to be acquired by a bigger company. Many members of the management came from ALZA Corporation, which was one of the most successful mergers in the above list. Hopes of adagrasib getting approval have increased after Amgens (NASDAQ:AMGN) KRASG12C inhibitor Lumakras received FDA approval for advanced NSCLC. RTT's Financial Newswire is relied upon by some of the world's largest financial institutions, including banks, brokerages, trading platforms and financial exchanges. In the wake of generic drugs eating into the sales of off-patent branded drugs, growing pressure from regulators to reduce the prices of drugs, drying pipelines, and ever-increasing R&D costs, there has been an increasing consolidation within the drug industry. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. The other candidates in the pipeline include CTX110, CTX120 and CTC130, all for immuno-oncology indications. There weren't that many biotech acquisitions in 2021, at least, not compared to other previous years. Date Acquirer Co. CRISPR has a licensing deal with cystic fibrosis specialist Vertex Pharmaceuticals worth more than a $900 million for this program. Last month, Adaptimmune announced that SPEARHEAD-1 trial evaluating afamitresgene autoleucel (afami-cel, formerly ADP-A2M4) in patients with advanced synovial sarcoma or myxoid/round cell liposarcoma (MRCLS) will meet its primary endpoint and data will be used to support biologics license application (BLA) filing for afami-cel next year. Who will buy? If you're going to give me a quick up-front profit, I'm definitely going to take it and I'm not going to complain about it. Sold GenPharm International, Inc. to Medarex, which was then acquired by Bristol-Myers Squibb (BMY): Mr. Rosen served as Director of Corporate Development at GenPharm International. Keith Speights: Let's switch gears. Acquisition rumors have swirled around specialty biotech BioMarin Pharmaceutical (NASDAQ: BMRN) for years now.In fact, Genetic Engineering & Biotechnology News has had it on its takeover target . Sold Kos Pharmaceuticals to Abbott Laboratories (ABT): Mr. Adams served as the President and Chief Executive Officer of Kos Pharmaceuticals, Inc. Abbott Laboratories bought out Kos Pharmaceuticals for $78 a share, or a 56% premium over the current share price. Biogen and Gilead Sciences would also do well to make some M&A deals this year. Given that the FDA is yet to approve a NASH drug, it is worth taking a risk with this one-trick pony. You Might Regret That, History Suggests the S&P 500 Could Soar in 2023. That remains to be seen. Ipsen bought out Tercica for $404M, or a 104% premium over the current stock price. Keith Speights owns Bristol Myers Squibb and Vertex Pharmaceuticals. Best Stocks & ETFs. 6. M&A deal flow dwindled in 2021, reflecting stricter antitrust laws. RTTNews.com for Company CEO Paul Wotton stated in the Antares 2nd quarter earnings call in 2012 that Pfizer approached Antares because it had a product on its shelf for three years which Antares might be able to help develop. Clovis Oncology is a commercial-stage biotechnology company whose lead drug is Rubraca, indicated for ovarian cancer. The company did have its fair share of troubles when the FDA rejected its application for Ocaliva in NASH, and late last year the company withdrew its application filed with the European Medicines Agency for the same. Sales of Vascepa have been growing, and in October of this year, an independent drug price watchdog group, Institute for Clinical and Economic Review (ICER), released a report that shows Vascepa as cost-effective for CV risk reduction. Therefore, I am picking 5 best Mid-cap biotech acquisition targets in this post with deal value less than $10B each. The company's portfolio consists of a few commercialized products and multiple clinical and pre-clinical product candidates. These ASOs regulate the expression of a specific factor, which if present causes a particular disease. No. Learn More. Cambrex today announced that it has completed its acquisition of Snapdragon Chemistry. The company has a team of world-class researchers, trying to transform the company-owned CRISPR/Cas9 gene-editing platform into breakthrough human therapeutics. Mergers and acquisitions occur frequently in the biopharmaceutical industry. Acquirer Ticker Acquired Ticker Deal value Price/Share Notes Link to the news PR; 01/05/2021: Hologic, Inc. HOLX: Private-German co. $64M-leader in biopsy site markers: https://bwnews.pr/2L3d7lF: If they can get taken out by even higher prices, I think that would be great for the investors. We first began to hear acquisition rumors in Antares in late 2011. Clovis Oncology is an American pharmaceutical company specialized in oncology treatments. While 2022 started rather quiet as it pertains to M&A, the second quarter was one of the busiest three-month periods for acquisitions in recent years. Aesther Healthcare Acquisition Corp and Ocean Biomedical, Inc. announced that AEHA has filed with the U.S. Securities and Exchange Commission a definitive proxy statement in connection with its proposed business combination with Ocean and with respect to the special meeting of Aesthers stockholders scheduled to be held on February 3, 2023. The best transactions benefit the shareholders of both the acquiring company and the takeover target. In 2021, more than a dozen biotech companies have been snapped by big pharmaceutical companies. Seagen has quite a few oncology drugs that would work well with the Bristol-Myers drugs. The companies are already partners for CRISPR's beta-thalassemia and sickle cell therapy. Otrexup needs a doctor's prescription and cannot be purchased over the counter. It expects to grow its revenues by 14% in the next fiscal year. The biotech sector saw another strong session Tuesday, and while the broad rally lifted the entire group, the action in some names was being driven by takeover rumors. In addition, the Americans have multiple clinical-stage programs in immuno-oncology and regenerative medicine that could provide new assets for big pharmaceutical companies. If the Juno acquisition rumors turn out to be true, this will be the second acquisition . I'm thinking Intellia (NTLA -1.57%) potentially being acquired by Regeneron (REGN 0.83%), and CRISPR Therapeutics (CRSP 3.66%) potentially being acquired by Vertex Pharmaceuticals (VRTX 3.67%). Dear MULN Stock Fans, Brace Yourself for a Reverse Stock Split, 5 Under-the-Radar Penny Stocks With 100% Upside Potential, 3 Stocks Set to Soar When the Bears Get Short-Squeezed, 3 Troubled Tech Stocks to Buy For The Long Haul, 3 AI Stocks That Will Make You Amazingly Rich in 10 Years, Attractive & promising pipeline/technology. 9. *Stock Advisor returns as of January 10, 2022. Only one year later, the company was granted FDA approval for Myfembree (relugolix) in combination with two hormone drugs as the first once-daily treatment for heavy menstrual bleeding linked to uterine fibroids in premenopausal women, with a treatment duration for up to two years. 11. To make the world smarter, happier, and richer. When the symbol you want to add appears, add it to My Quotes by selecting it and pressing Enter/Return. 10 stocks we like better than Vertex PharmaceuticalsWhen our award-winning analyst team has a stock tip, it can pay to listen. This management team has time and time again sold companies for nice premiums. (RTTNews) - 2019 saw more than 25 acquisition deals being executed in the biotech sector, of which 14 were billion-dollar deals. On January 9, 2023, Biotech Acquisition Company (the "Company") received written notice (the "Notice") from the Listing Qualifications Department of The Nasdaq Stock Market LLC ("Nasdaq") indicating that the Company is not in compliance with Nasdaq Listing Rule 5620(a), due to the . And M&A activity still looks fairly lively in 2020 despite a somewhat subdued start . Leading gene-editing biotechs CRISPR Therapeutics and Intellia are likely to be acquired at some point. To read this article on Zacks.com click here. The FDA has imposed a clinical hold on this gene therapy candidate that is being evaluated for a condition called phenylketonuria. BioNTech Strengthens Its Artificial Intelligence With Acquisition Of British . Moreover, companies investing in mRNA technology are gaining a lot of attention, given the success of the technology in the development of COVID-19 vaccines. If you have an ad-blocker enabled you may be blocked from proceeding. Zacks Investment Research, Alnylam Pharmaceuticals, Inc. (ALNY) : Free Stock Analysis Report, Biogen Inc. (BIIB) : Free Stock Analysis Report, BioMarin Pharmaceutical Inc. (BMRN) : Free Stock Analysis Report, Adaptimmune Therapeutics PLC (ADAP) : Free Stock Analysis Report, CRISPR Therapeutics AG (CRSP) : Free Stock Analysis Report. We have been hearing some strong acquisition rumors concerning AcelRx, much like we heard about Obagi last year. While an attractive pipeline candidate is a key lure for these companies, cost synergies in research and development are an added benefit as quite a few smaller biotech companies are using innovative technologies to develop drugs and treatments. Premiums were calculated using the acquired company's share price at the previous trading day's close, Only one therapeutic category is counted for each acquired company. I think that would potentially drive sales of Opdivo. The Cambridge, Massachusetts-based biopharma has three commercial products on the market. I think these would be great for the investors, mostly because I think maybe their valuations are a little inflated. If all goes well as planned, the Company will have another drug on the market - Pemigatinib - as a treatment for Cholangiocarcinoma, a rare cancer that forms in the bile duct. Just recently, Bayer bought out Conceptus for $1.1B. Elicio Therapeutics, a privately-held, clinical-stage biotechnology company developing a pipeline of novel immunotherapies for the treatment of cancer and other diseases, has entered into a definitive merger agreement with Angion Biomedica Corp under which Elicio will merge with a wholly-owned subsidiary of Angion in an all-stock transaction. Many of today's most influential medicines, from the life-saving cancer treatment Keytruda to the anti-inflammatory agent Humira, might not have become so without mergers and acquisitions. According to Glenn Hunzinger, U.S. Pharmaceutical & Life Sciences Consulting Solutions Leader at PricewaterhouseCoopers. 4 Biotechs That Could Be Potential Acquisition Targets in 2021. Targeted indications include cardio-renal, metabolic, neurological, infectious diseases, cancer, ophthalmology, pulmonary & allergy and hematology. According to a report by Implement Consulting Group, a Scandinavian consultancy, "on average only 62% of the M&A deals are successful. Alnylam currently carries a Zacks Rank #3 (Hold). The 10 top takeover targets a biotech buyout that you would really like see! Out Tercica for $ 1.1B three years since the PARP inhibitor has been involved in thirteen different.! Rank # 3 ( hold ) Myers Squibb and Vertex Pharmaceuticals the world smarter,,. It expects to grow its revenues by 14 % in the biopharmaceutical industry to biotech acquisition rumors a NASH,! In Oncology treatments with the Bristol-Myers drugs in this post with deal value than... Were n't that many biotech acquisitions in 2021, at least, compared. Acelrx, much like we heard about Obagi last year well with Bristol-Myers... ( GILD -1.00 % ) also has a host of investigational therapeutics Amgens ( Nasdaq AMGN. 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